NSC 179884

NSC 179884 - Names and Identifiers

Name	(22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione
Synonyms	Withanone WITHANONE NSC 179884 WITHANONE(SH) WITHANONE(SH)(NEW) Withanone 27570-38-3 (22R)-6α,7α-Epoxy-5,17,22-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid δ-lactone (5a,6a,7a,22R)-6,7-Epoxy-5,17,22-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid d-lactone
CAS	27570-38-3

NSC 179884 - Physico-chemical Properties

Molecular Formula	C28H38O6
Molar Mass	470.6
Density	1.264
Boling Point	653.7±55.0 °C(Predicted)
Flash Point	216℃
Appearance	neat
pKa	12.98±0.70(Predicted)
Storage Condition	2-8°C

NSC 179884 - Risk and Safety

WGK Germany

NSC 179884 - Introduction

(22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione is a natural product produced by the fermentation of a plant with the chemical name (22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione. It has a variety of biological activities and pharmacological effects, and is widely used in traditional Chinese medicine and herbal preparations.

(22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione has certain antioxidant activity and can help protect cells from free radical damage. In addition, it also has anti-inflammatory, anti-tumor, antibacterial, improve cognitive function, anti-anxiety and other pharmacological activities.

(22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione are mainly prepared by natural plant extraction and chemical synthesis. The natural plant extraction method is by extracting plants containing (22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione, such as Indian ginseng, etc, the purified (22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione is then obtained by chemical and physical treatment. The chemical synthesis method is to synthesize the structure of (22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione by chemical reaction and synthetic route.

Regarding safety,(22R)-5α,17α-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione are considered to be relatively safe natural products, however, it is still necessary to pay attention to the appropriate dosage and method of use to avoid potential adverse reactions. Long-term and high-dose dosage may cause some side effects, such as gastrointestinal discomfort, dizziness, insomnia, indigestion, etc. It is best to consult the advice of a doctor or professional when using it, and follow the correct dosage and application method.

Last Update：2024-04-09 21:54:55